Stress, pain, and anxiety relief

Meet Pro-Nox™


Pro-Nox™ was developed over a decade ago with the clear vision of benefiting practitioners and their patients at the forefront of medicine. Pro-Nox™ is an FDA cleared analgesia that delivers 50% Nitrous Oxide and 50% Oxygen. Best known for its ability to safely and effectively ease pain, anxiety, and discomfort, Pro-Nox™ is the leading pneumatically-driven gas delivery system on the market for medical and aesthetic patients. Pro-Nox™ provides more than just pain relief. By improving the patient experience during treatment, and in the provider's office, practitioners are better equipped to perform procedures that deliver optimal results—while ensuring that all patients are in their “Pro-Nox™ Comfort Zone.”

Pro-Nox™ is a Big Deal
As Seen In…

Perfect 50/50 Mixture

Safety First


Using an ideal combination of 50/50 Nitrous Oxide and Oxygen, Pro-Nox™ is the analgesia of choice for over 6,000+ practices across the United States and Canada. Plus, with Pro-Nox™, practitioners can have peace of mind as they work, while patients feel more at ease during treatments. 

Analgesics, often referred to as “pain relievers,” include common drugs like aspirin, ibuprofen, or acetaminophen. Pro-Nox™ is a 100% self-administered N2O and O2 gas delivery system, producing effects which most practitioners and patients describe as “similar to laughing gas.” Unlike anesthesia (which halts the brain and body’s nerve signals), analgesia temporarily blocks the body’s pain signals from reaching the brain, and disassociates the brain’s ability to even process pain signals.

Pro-Nox™ was designed to support a variety of specialties as their pain and anxiety management solution for all treatment offerings, including: plastic surgery, dermatology, medical aesthetics, obstetrics-gynecology, urology, labor and delivery, ambulatory care, orthopedics, regenerative medicine, hospitals, surgery centers, and more!

Pro-Nox™ Is Making An Impact

30,000 Circuits Sold Per Month

Over1.5 Million Treatments

7,000+ Practices

Better Together

Pro-Nox™ Is Powered By:


CAREstream America is THE Pro-Nox™ distributor! It began in 2013 as an offshoot of the #1 respiratory company in Canada: CAREstream Medical. CAREstream America was formed to provide innovative solutions and devices to help clinicians enhance, elevate, and exceed… whether you specialize in orthopedics, aesthetics, hospital care, urology, OB-GYN or regenerative medicine, to name a few. Learn more about our premier partner and its cutting-edge offerings by visiting www.carestreamamerica.com.

CAREstream America

Become a Pro-Nox™ Comfort Zone