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Pro-Nox™ is a proven, safe analgesic gas delivery system that utilizes a 50/50 mix of Nitrous Oxide and Oxygen. In simpler terms, Pro-Nox™ is comparable to “laughing gas” because it relieves treatment pain, stress, anxiety, and overall discomfort by safely inducing a more relaxed and euphoric state of being.

Pro-Nox™is inhaled using interchangeable breathing circuits, ensuring complete protection against germs and other viral bacteria. With our additional PharmaMini filter, patients can receive a supplementary layer of up to 99.99% viral protection.

Patients are in complete control when using Pro-Nox™. Our demand valve allows for 100% self-administration, ensuring maximum safety for patients and staff — however much pain or anxiety relief you need is however much you breathe in. All Pro-Nox™ Comfort Zones are staffed with specially trained professionals who will guide you through the inhalation process.

Yes! Pro-Nox™ is FDA cleared and the most trusted pain management solution for over 5,500 offices in the United States and Canada! Unlike anesthesia, Pro-Nox™ does NOT cause patients to fall into complete sedation or “go under.” Instead, its analgesia elicits temporary pain relief without losing total consciousness, sense of feeling, and/or movement during your procedure.

In fact, Pro-Nox™ has been a popular, trusted addition for use in labor and delivery. So if it is safe for mothers and their unborn children, then you can rest assured Pro-Nox™is safe for you!

Upon your initial 5-7 breaths of Pro-Nox™, most patients describe what they feel next as being “like on Cloud Nine.” All of their pre-treatment stress, procedure pain and general discomfort fades away. They suddenly feel lighter, calmer, and ready to confidently undergo any treatment! And of course, some patients will feel like they’ve taken laughing gas and become more giggly and happy.

Initially, Pro-Nox™ was actually intended for use in labor and delivery. Since it has been proven to be safe and effective for expecting mothers and their unborn children, Pro-Nox™ is certainly safe for you! Almost anyone is the perfect candidate for Pro-Nox™, especially if you’re feeling anxious about treatment, hate needles, or are unsure of undergoing a treatment that seems painful. Consult with a Pro-Nox™ Comfort Zone near you to accurately gauge whether you are an ideal candidate for Pro-Nox™. Of course, your provider will review the contraindications.

Some patients describe feeling as though they’ve had a few cocktails, like a “happy buzz,” or they feel extremely relaxed. Others become a little “giggly” and bubbly. You will notice a slight deepening in your voice after initial administration. In rare cases, patients may feel a bit light-headed. Overall, Pro-Nox™ provides an anti-anxiety effect, making you feel as comfortable and laid back as you would at the beach or spa.

Yes! Once your medical or aesthetic procedure is complete, the analgesic effects of Pro-Nox™ will diminish within about 10-15 minutes. One of patients’ (and doctors’!) favorite things about Pro-Nox™ is that it is short-lasting, so you can come in for treatment and safely drive yourself home, return to work, etc. without a problem.

There is never a 100% guarantee that you will feel absolutely no pain. Most Pro-Nox™ patients report up to an 85% reduction in pain and/or anxiety — making any of their medical or aesthetic treatments a breeze.

Pro-Nox™ is the perfect pair to a wide variety of aesthetic, medical, and regenerative treatments. It is most commonly used in medical aesthetics for Radiofrequency Microneedling (RFMN), Fractional CO2 laser treatments, injectables, and more. However, Pro-Nox™ is also effective when used in regenerative medicine and core practices for PRP (platelet-rich plasma) injections, urology procedures like vasectomies and prostate biopsies, and even obstetrics-gynecology and labor and delivery!